About me
Enthusiastic physiotherapist and researcher
I am a sports physiotherapist, doctor in motor sciences and a researcher at the Cliniques universitaires Saint-Luc in Brussels, Belgium. I have long been interested in the interactions between physical activity and health and am also co-founder of the Da Vinci Health, an exercise medicine centre that allows unconditioned people to get back to physical activity in a supervised and safe way. I am also a world-travelling lecturer and author of numerous scientific publications on the importance of physical activity and physiotherapy in the treatment of chronic musculoskeletal diseases such as hemophilia.

Details
Name :
Sébastien Lobet
Age :
44 years
Location :
Brussels, Belgium
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Despite the fact that joint bleeds (haemarthrosis) frequently occur in people with haemophilia (PwH) with invalidating arthropathies as result, the clinical pain experience has received only limited attention
A sudden increase in pain intensity can be linked to a bleed, but in most cases, no acute bleed is confirmed. Nevertheless, a patient’s perception of an acute bleed as cause of the pain might impact the patients’ behaviour in response to pain. It is therefore essential to gain more insight into pain coping strategies seen in PwH. Aim: This systematic review aims to identify the range of pain coping behaviour strategies used among PwH and the factors associated with pain coping behaviour. Methods: This review was reported according to the Preferred Reporting Items for Systematic reviews and Meta-analyses guidelines (PRISMA). PubMed andWeb of Science were systematically screened for relevant literature using keyword combinations related to adult PwH, pain and pain coping behaviour strategies. Risk of bias was assessed with the modified Newcastle-Ottowa Scale. Results: Eleven full text articles (nine cross-sectional and two comparative studies) consisting of 1832 PwH met the inclusion criteria. Due to the heterogeneity of the study samples, quality of evaluation instruments and varying risk of bias, it was difficult to draw conclusions regarding the used pain coping behaviour strategies and associated factors. Conclusion: Literature on pain coping behaviour strategies and associated factors in PwH is still scarce and describes heterogenous results. Validated haemophilia-specific instruments are warranted to inventory pain coping behaviour in a standardized way.
Request
Ankle arthropathy is highly prevalent among people with haemophilia (PwH), even with prophylaxis, and leads to pain and disability. Mechanisms and consequences of painful symptoms related to ankle arthropathy have not been extensively studied.
Request
The Hemophilia Joint Health Score (HJHS) was developed and validated to detect arthropathy in children. Additional evidence is required to show validity in adults. We studied the convergent and discriminant construct validity of the HJHS version 2.1(HJHSv2.1) in adults with hemophilia
Request
Episodes of bleeding in patients with haemophilia (PwH) are associated with haemophilic arthropathy, limitations in physical performance, reduced quality of life (QoL), and gait disorders.
Aim: This non-randomized, controlled, interventional, prospective, single-centre pilot study aimed to assess the effects of an 8-week supervised therapeutic exercise program on musculoskeletal health, gait kinematic parameters (GKP), functional capacity, and QoL in adult PwH. Methods: Nineteen PwH were allocated to an exercise group (n = 10) or a control group (n = 9). The patients in the exercise group followed an 8-week supervised therapeutic exercise program. The Haemophilia Joint Health Score (HJHS), a twodimensional video-based gait kinematic analysis (2D-GKA), the 6-min walking test (6MWT), and the Haemophilia Quality of Life Questionnaire for Adults (Haem-A-Qol) were used as the outcome measures at baseline, after the exercise program(at the 8th week), and at the 6th-month follow-up. Results: A significant improvement was observed in the exercise group in the HJHSTotal and Haem-A-Qol Total scores and the 6MWT value after the exercise program. Moreover, the 2D-GKArevealed improvement in most of theGKP(knee extension during the midstance and late swing phases, ankle dorsiflexion during the midstance phase, and ankle plantar flexion during the preswing phase). However, the gain obtained by the exercise program was not maintained at the 6th-month follow-up for the HJHSTotal and Hem-A-QoL-Total scores and GKP. Conclusion: The 8-week supervised therapeutic exercise program was successful
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