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Feasibility and outcomes of low-dose and low-frequency prophylaxis with recombinant extended half-life products (Fc-rFVIII and Fc-rFIX) in Ivorian children with hemophilia: Two-year experience in the setting of World Federation of Haemophilia humanitarian aid programme

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Introduction: In sub-Saharan Africa, access to clotting factor concentrates (CFCs) is often extremely limited and published data on people with haemophilia on prophylaxis are almost not existent.

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Comprehensive care on paper only? The challenge for physiotherapy provision in day to day haemophilia practice

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Dear Editor: Comprehensive care for people with haemophilia (PWH) is endorsed by the World Federation of Haemophilia (WFH), and it is now the preferred model of care provision for people with inherited bleeding disorders.

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Paediatric patients with blood-induced ankle joint arthritis demonstrate physiological foot joint mechanics and energetics during walking

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Aim: To compare foot joint kinetics and energetics in male paediatric boys with and without blood-induced ankle joint destruction to these of matched control groups.

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European principles of inhibitor management in patients with haemophilia: implications of new treatment options

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The emerging clinical and scientific role of the physiotherapist in haemophilia care.

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Given these specialized skills, a combined haemophilia-physiotherapy approach should be highly encouraged , along with international networks like the European Association for Haemophilia and Allied Disorders Physiotherapy Committee and the World Federation of Haemophilia Musculoskeletal Committee to support …

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Acquired multi-segment foot kinematics in haemophilic children, adolescents and young adults with or without haemophilic ankle arthropathy.

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Introduction and aim: The ankle joint remains vulnerable in children with haemophilia and is the primary joint affected. The purpose of this study was to dynamically characterize the segmental foot and ankle kinematics of male children, adolescents and young adults with or without ankle arthropathy.

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Clinical gait features are associated with MRI findings in patients with haemophilic ankle arthropathy.

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Introduction: Haemophilic ankle arthropathy due to repeated joint bleeds often leads to altered gait in adult patients with haemophilia.

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Practical Guidance for Non- Specialist Physical Therapists Managing People with hemophilia and Musculoskeletal Complications.

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People with hemophilia (PWH) have impaired blood coagulation and hemostasis. Bleeding into joints and muscles is the main manifestation of the disorder, causing severe joint damage and muscle complications.

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The biomechanical behaviour of ankle and foot joints during walking with shoes in patients with haemophilia.

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Introduction: Patients with haemophilia (PwH) often prefer shod walking over barefoot walking as footwear offers ankle joint stability and comfort during gait.

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Cross-cultural adaptation and validation of the Canadian Haemophilia Outcomes-Kids’ Life Assessment Tool (CHO-KLAT) in Côte d’Ivoire (the Ivory Coast)

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Health-related quality of life evaluation is recognized as an important outcome in the assessment of boys with haemophilia.

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Le rôle de la kinésithérapie (physiothérapie) dans le suivi de l’hémophilie : l’indispensable complément

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Si l’hémophilie est une maladie hématologique caractérisée par un déficit partiel ou complet du facteur VIII ou IX de la coagulation, ses complications hémorragiques affectent avant tout le système musculosquelettique.

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Cross-cultural adaptation and validation of Haem-A-QoL in Côte d’Ivoire

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Introduction: Health-related quality (HRQoL) evaluations are considered essential outcomes in the assessment of people with haemophilia.

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Blood-induced cartilage damage alters the ankle joint load during walking.

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Ankle cartilage damage due to repeated joint bleeds often leads to altered gait in adult patients with hemophilia. It is therefore of clinical importance to develop an understanding of the biomechanical gait features in hemophilia patients with and without blood-induced cartilage damage and age-matched control subjects.

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Development and evaluation of appropriate, culturally adapted educational tools for Ivorian patient with haemophilia, haemophilia carriers and their families

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Introduction: Patient education is the cornerstone of the management of chronic diseases like haemophilia.

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Implementation and assessment of a self- and community-based rehabilitation programme in patients with haemophilia from Côte d’Ivoire.

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Introduction: In resource‐constrained countries, few patients with haemophilia (PWH) have access to clotting factor concentrates (CFC), with increased musculoskeletal (MSK) complications.

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Scope of practice of haemophilia physiotherapists: a European survey.

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Introduction: European guidelines on the care of haemophilia recommend ready access to a range of services provided by a multidisciplinary team of specialists including physiotherapy.

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Haemophilia in Côte d’Ivoire (the Ivory Coast) in 2017: Extensive data collection as part of the World Federation of Hemophilia’s twinning programme.

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Introduction: In sub‐Saharan African countries, research on haemophilia is limited.

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Hemophilia carrier’s awareness, diagnosis, and management in emerging countries: a cross-sectional study in Côte d’Ivoire (Ivory Coast)

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Little data is available on awareness of hemophilia carrier condition or associated bleeding risk and management in Sub-Saharan African countries.

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Impact de l’activité physique sur trois comorbidités liées à l’hémophilie

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Dans cet article, nous passons en revue trois comorbidités qui peuvent non seulement influer sur la capacité d’un patient à participer à une AP,

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Recommendations on multidisciplinary management of elective surgery in people with haemophilia.

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Planning and undertaking elective surgery in people with haemophilia (PWH) is most effective with the involvement of a specialist and experienced multidisciplinary team (MDT) at a haemophilia treatment centre.

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Postural control during a transition task in haemophilic children, adolescents and young adults with haemophilic ankle arthropathy.

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Background: The aim of this study was to determine whether young haemophilic boys with and without MRI-based signs of ankle arthropathy demonstrate reduced balance ability during a transition task with eyes open and eyes closed.

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Assessment of passive musculoarticular ankle stiffness in children, adolescents and young adults with haemophilic ankle arthropathy.

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Objectives: To measure passive musculoarticular ankle stiffness (PMAAS) and its intra- and interday reliability in adult control subjects without ankle disorders.

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European principles of inhibitor management in patient with haemophilia.

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Background: In spite of recent major advances in the understanding and treatment of inhibitor development in patients with haemophilia, multidisciplinary management of many of these patients remains suboptimal and highly heterogenous across Europe.

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Reliability and clinical features associated with the IPSG MRI tibiotalar and subtalar joint scores in children, adolescents and young adults with haemophilia.

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Objectives: To assess the reliability of the IPSG MRI scale for tibiotalar (TTJ) and subtalar joint (STJ) changes in young haemophilic patients, correlating MRI findings with functional scores and 3D-rearfoot kinematics.

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Deficits of ankle muscle strength not found in children, adolescents and young adults with haemophilic ankle arthropathy.

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Objectives: Adequate management of haemophilia patients requires early detection of joint impairment in relatively asymptomatic patients.

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Biomechanical markers and theoretical concepts related to hemophilic ankle and subtalar joint arthropathy: introducing the term “hemophilic tarsal pan-arthropathy”.

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Objectives: Background: Although regular factor replacement can reduce the incidence of joint bleeds and slow down the development of haemophilic arthropathy, the ankle joint remains particularly vulnerable even in children with haemophilia on primary or secondary prophylaxis and is now the primary joint affected.

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3D mutisegment foot kinematics in children: A developmental study in typically developing boys.

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Background: The relationship between age and 3D rotations objectivized with multisegment foot models has not been quantified until now.

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Postural control of typical developing boys during the transition from double-leg stance to single-leg stance.

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Literature is lacking information about postural control performance of typically developing children during a transition task from double-leg stance to single-leg stance.

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The Second Team Haemophilia Education Meeting, 2016, Frankfurt, Germany.

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The first Team Haemophilia Education (THE) Meeting was held on 7-8 May 2015 in Amsterdam, The Netherlands. It aimed to promote the optimal care of patients with haemophilia through education of the multidisciplinary treatment team.

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Stop only advising physical activity in adults with haemophilia… prescribe it now! The role of exercise therapy and nutrition in chronic musculoskeletal diseases.

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In the past, patients with haemophilia (PWH) have been advised against participation in physical activity. It is now recognized that properly managed exercise and participation in appropriate sports can be highly beneficial for them.

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Partnering to change the world for people with haemophilia: 6th Haemophilia Global Summit, Prague, Czech Republic, 24–26th September 2015.

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The 6(th) Haemophilia Global Summit was held in Prague, Czech Republic, in September 2015.

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L’analyse quantifiée de la marche: principes et applications cliniques.

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La marche est une succession de mouvements cycliques répétitifs avec des déplacements s’effectuant dans les trois plans de l’espace.

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Managing Haemophilia for life: 5th Haemophilia Global Summit.

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The 5th Haemophilia Global Summit was held in Barcelona, Spain, in September 2014.

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Managing haemophilia for life: 4th haemophilia global summit.

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The 4th Haemophilia Global Summit was held in Potsdam, Germany, in September 2013 and brought together an international faculty of haemophilia experts and delegates from multidisciplinary backgrounds.

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Optimal management of hemophilic arthropathy and hematomas.

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Hemophilia is a hematological disorder characterized by a partial or complete deficiency of clotting factor VIII or IX.

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The benefits of exercise for patients with haemophilia and recommendations for safe and effective physical activity.

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Most health care professionals involved in the management of people with haemophilia (PWH) believe that exercise is beneficial and its practice is widely encouraged. This article aims to demonstrate that appropriate exercise (adapted to the special needs of the individual PWH) may be beneficial for all PWH through improved physical, psychosocial and medical status.

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Three-Dimensional Gait Analysis Can Shed New Light on Walking in Patients with Haemophilia.

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In patients with haemophilia, the long-term consequences of repeated haemarthrosis include joint cartilage damage and irreversible chronic arthropathy, resulting in severe impairments in locomotion.

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Impact of multiple joint impairments on the energetics and mechanics of walking in patients with haemophilia.

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Few studies have assessed the changes produced by multiple joint impairments (MJI) of the lower limbs on gait in patients with haemophilia (PWH).

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Functional assessment of haemophilic arthropathy with three-dimensional gait analysis.

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In patients with haemophilia, the long-term consequences of repeated haemarthrosis include joint cartilage damage and irreversible chronic arthropathy, resulting in severe impairments in locomotion.

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Impact of ankle osteoarthritis on the energetic and mechanics of gait: The case of hemophilic arthropathy.

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Background: Osteoarthritis may affect joints in any part of the body, including the ankle. The purpose of this study was to assess the impact of ankle osteoarthritis on the energetics and mechanics of gait, while taking into account the effect of slower speed generally adopted by patients with osteoarthritis.

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Functional impact of custom-made foot orthoses in patients with haemophilic ankle arthropathy.

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Although foot orthoses are often prescribed to patients with haemophilia (PWH) and ankle arthropathy, the efficacy and biomechanical effects of such devices are not fully understood.

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De behandeling van hemartrose bij hemofiliepatienten: Deel 1 pathofysiologie en diagnose. Deel 2 therapie

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Hemofilie is een bloedziekte die wordt gekenmerkt door een partiële of volledige factor VIII- of factor IX-deficiëntie en die vooral bloedingen veroorzaakt in spieren en gewrichten.

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La prise en charge des hémarthroses chez les patients hémophiles. Partie 1: pathophysiologie et diagnostic. Partie 2: Traitement

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Si l’hémophilie est une maladie hématologique caractérisée par un déficit partiel ou complet du facteur VIII ou IX de la coagulation, ses complications hémorragiques affectent avant tout le système musculo-squelettique.

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Body structure versus body function in haemophilia: the case of haemophilic ankle arthropathy.

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Background: Imaging and clinical scores are the main tools used to evaluate the progression of haemophilic arthropathy (HA). Based on haemophilic ankle arthropathy, this study aimed to explore the concordances between structural and clinical alterations, determined by standard radiological and clinical scores, and functional alterations assessed by three-dimensional gait analysis (3DGA).

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Natural progression of blood-induced joint damage in patients with haemophilia: clinical relevance and reproducibility of three-dimensional gait analysis.

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A major complication in haemophilia is the destruction of joint cartilage because of recurrent intraarticular and intramuscular bleeds.

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Subclinical deep venous thrombosis observed in 10% of haemophilic patients undergoing major orthopaedic surgery.

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Deep venous thrombosis (DVT) is a common postoperative complication in patients undergoing major orthopedic surgery of the lower limbs, such as total hip replacement, total knee replacement or hip fracture surgery.

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The role of physiotherapy after Total Knee Arthroplasty in patients with haemophilia.

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With the availability of clotting factor concentrates, advances in surgical techniques, better implant design, and improvements in postoperative management, total knee arthroplasty has become the treatment of choice for haemophilia patients suffering from end-stage haemophilic knee arthropathy.

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Physiotherapy following elective orthopaedic procedures.

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As haemophilic arthropathy and chronic synovitis are still the most important clinical features in people with haemophilia, different kinds of invasive and orthopaedic procedures have become more common during the last decades.

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Outcome assessment in osteoarthritic patients undergoing total knee arthroplasty.

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The purpose of this study was to better understand the relationship between knee pain, locomotor functional status, and health-related quality of life (HRQoL) outcomes in osteoarthritic (OA) patients undergoing primary total knee arthroplasty (TKA).

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